Role of plants in anticancer drug discovery
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چکیده
منابع مشابه
EDITORIALS Anticancer Drug Discovery
The National Cancer Institute's (NCI's) human tumor cell line panel for screening potential new anticancer drugs is now operational (/). Its implementation and the demonstration of its feasibility represent a technical and organizational tour de force. The rationale for the change in the primary screen from leukemias in mice to the array of 60 human cancer cell lines was earlier debated in cont...
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Current research in drug discovery from medicinal plants involves a multifaceted approach combining botanical, phytochemical, biological, and molecular techniques. Medicinal plant drug discovery continues to provide new and important leads against various pharmacological targets including cancer, HIV/AIDS, Alzheimer's, malaria, and pain. Several natural product drugs of plant origin have either...
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Small organic molecules derived from higher plants have been one of the mainstays of cancer chemotherapy for approximately the past half a century. In the present review, selected single chemical entity natural products of plant origin and their semi-synthetic derivatives currently in clinical trials are featured as examples of new cancer chemotherapeutic drug candidates. Several more recently ...
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F.E. Koehn (ed.), Natural Products and Cancer Drug Discovery, Cancer Drug Discovery and Development, DOI 10.1007/978-1-4614-4654-5_7, © Springer Science+Business Media New York 2013 Abstract Genetic engineering is the process of altering, in a premeditated fashion, the genetic makeup of an organism and has started to play an increasing role in the production and development of clinically signi ...
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ژورنال
عنوان ژورنال: Phytochemistry Letters
سال: 2014
ISSN: 1874-3900
DOI: 10.1016/j.phytol.2013.11.010